Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen

T cells recognizing epitopes on the surface of mycobacteria-infected macrophages can impart protection, but with associated risk for reactivation to lung pathology. We aimed to identify antibodies specific to such epitopes, which carry potentials for development toward novel therapeutic constructs....

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ortega, Paola A., Silva-Miranda, Mayra, Torres-Larios, Alfredo, Campos-Chávez, Eduardo, Franken, Kees C. L. C. M., Ottenhoff, Tom H. M., Ivanyi, Juraj, Espitia, Clara
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564862/
https://ncbi.nlm.nih.gov/pubmed/33117380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.577815
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