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AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin

GH (growth hormone) secretion/action is modulated by alterations in energy homeostasis, such as malnutrition and obesity. Recent data have uncovered the mechanism by which hypothalamic neurons sense nutrient bioavailability, with a relevant contribution of AMPK (AMP-activated protein kinase) and mTO...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Vázquez, María J., Novelle, Marta G., Rodríguez-Pacheco, Francisca, Lage, Ricardo, Varela, Luis, López, Miguel, Pinilla, Leonor, Tena-Sempere, Manuel, Diéguez, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564832/
https://ncbi.nlm.nih.gov/pubmed/32839401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091940
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