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CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells

SIMPLE SUMMARY: Here we show that a protein called C/EBPδ is present in healthy pancreas tissue but almost absent in pancreas tumors. Patients with less C/EBPδ in their tumors had the most metastases and the worst survival chances, showing that C/EBPδ has tumor-suppressive properties in pancreatic c...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Hartl, Leonie, Duitman, JanWillem, Aberson, Hella L., Chen, Kan, Dijk, Frederike, Roelofs, Joris J.T.H., Dings, Mark P.G., Hooijer, Gerrit K.J., Hernanda, Pratika Y., Pan, Qiunwei, Busch, Olivier R., Besselink, Marc G.H., Boerman, Ton, Peppelenbosch, Maikel P., Bijlsma, Maarten F., Spek, C. Arnold
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564797/
https://ncbi.nlm.nih.gov/pubmed/32906832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092546
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