CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells

SIMPLE SUMMARY: Here we show that a protein called C/EBPδ is present in healthy pancreas tissue but almost absent in pancreas tumors. Patients with less C/EBPδ in their tumors had the most metastases and the worst survival chances, showing that C/EBPδ has tumor-suppressive properties in pancreatic c...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Hartl, Leonie, Duitman, JanWillem, Aberson, Hella L., Chen, Kan, Dijk, Frederike, Roelofs, Joris J.T.H., Dings, Mark P.G., Hooijer, Gerrit K.J., Hernanda, Pratika Y., Pan, Qiunwei, Busch, Olivier R., Besselink, Marc G.H., Boerman, Ton, Peppelenbosch, Maikel P., Bijlsma, Maarten F., Spek, C. Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564797/
https://ncbi.nlm.nih.gov/pubmed/32906832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092546
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