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Early macrophage infiltrates impair pancreatic cancer cell growth by TNF-α secretion
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a grim disease with high mortality rates. Increased macrophage influx in PDAC is a common hallmark and associated with poor prognosis. Macrophages have high cellular plasticity, which can differentiate into both anti- and pro-tumorigenic propert...
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| Publié dans: | BMC Cancer |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7709323/ https://ncbi.nlm.nih.gov/pubmed/33267818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07697-1 |
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