The Receptor Tyrosine Kinase TrkA Is Increased and Targetable in HER2-Positive Breast Cancer

The tyrosine kinase receptor A (NTRK1/TrkA) is increasingly regarded as a therapeutic target in oncology. In breast cancer, TrkA contributes to metastasis but the clinicopathological significance remains unclear. In this study, TrkA expression was assessed via immunohistochemistry of 158 invasive du...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Griffin, Nathan, Marsland, Mark, Roselli, Severine, Oldmeadow, Christopher, Attia, John, Walker, Marjorie M., Hondermarck, Hubert, Faulkner, Sam
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564775/
https://ncbi.nlm.nih.gov/pubmed/32957504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091329
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