The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung

The neurotrophic tyrosine kinase receptor TrkA (NTRK1) and its ligand nerve growth factor (NGF) are emerging promoters of tumor progression. In lung cancer, drugs targeting TrkA are in clinical trials, but the clinicopathological significance of TrkA and NGF, as well as that of the precursor proNGF,...

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Pubblicato in:Sci Rep
Autori principali: Gao, Fangfang, Griffin, Nathan, Faulkner, Sam, Rowe, Christopher W., Williams, Lily, Roselli, Severine, Thorne, Rick F., Ferdoushi, Aysha, Jobling, Phillip, Walker, Marjorie M., Hondermarck, Hubert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970205/
https://ncbi.nlm.nih.gov/pubmed/29802376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26408-2
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