A carregar...

ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels

Nerve growth factor (NGF) promotes the survival and differentiation of neurons. NGF is initially synthesized as a precursor, proNGF, which is the predominant form in the central nervous system. NGF and proNGF bind to TrkA/p75NTR to mediate cell survival and to sortilin/p75NTR to promote apoptosis. T...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ioannou, Maria S., Fahnestock, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372615/
https://ncbi.nlm.nih.gov/pubmed/28282920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030599
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!