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Receptor Tyrosine Kinase Signaling Mechanisms: Devolving TrkA Responses with Phosphoproteomics

Receptor tyrosine kinases (RTKs) function through protein kinase entities located in the intracellular domain of each protomer. Following activation by ligand binding, they selectively form phosphotyrosine residues by autocatalytic modification. Some of these sites are involved in maintaining the ac...

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Hlavní autoři: Bradshaw, R.A., Chalkley, R.J., Biarc, J., Burlingame, A. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577974/
https://ncbi.nlm.nih.gov/pubmed/23266087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2012.10.006
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