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Receptor Tyrosine Kinase Signaling Mechanisms: Devolving TrkA Responses with Phosphoproteomics

Receptor tyrosine kinases (RTKs) function through protein kinase entities located in the intracellular domain of each protomer. Following activation by ligand binding, they selectively form phosphotyrosine residues by autocatalytic modification. Some of these sites are involved in maintaining the ac...

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Bibliographic Details
Main Authors: Bradshaw, R.A., Chalkley, R.J., Biarc, J., Burlingame, A. L.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577974/
https://ncbi.nlm.nih.gov/pubmed/23266087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2012.10.006
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