Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation

Diabetic peripheral neuropathy (DPN) is caused by hyperglycemia, which induces oxidative stress and inflammatory responses that damage nerve tissue. Excessive generation of reactive oxygen species (ROS) and NOD-like receptor protein 3 (NLRP3) inflammasome activation trigger the inflammation and pyro...

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Publicado en:Cells
Main Authors: Cheng, Yu-Chi, Chu, Li-Wen, Chen, Jun-Yih, Hsieh, Su-Ling, Chang, Yu-Chin, Dai, Zen-Kong, Wu, Bin-Nan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564733/
https://ncbi.nlm.nih.gov/pubmed/32842536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091948
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