Maresin 1 Attenuates Radicular Pain Through the Inhibition of NLRP3 Inflammasome-Induced Pyroptosis via NF-κB Signaling

BACKGROUND: The exposure of the nucleus pulposus (NP) causes an immune and inflammatory response, which is intrinsically linked to the pathogenesis of radicular pain. As a newly discovered pro-resolving lipid mediator, maresin 1 (MaR1) could exert powerful inflammatory resolution, neuroprotection, a...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Wang, Yi-hao, Li, Yan, Wang, Jun-nan, Zhao, Qing-xiang, Jin, Jin, Wen, Shuang, Wang, Si-cong, Sun, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479972/
https://ncbi.nlm.nih.gov/pubmed/32982664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00831
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