Adjuvantation of an Influenza Hemagglutinin Antigen with TLR4 and NOD2 Agonists Encapsulated in Poly(D,L-Lactide-Co-Glycolide) Nanoparticles Enhances Immunogenicity and Protection against Lethal Influenza Virus Infection in Mice

Along with their excellent safety profiles, subunit vaccines are typically characterized by much weaker immunogenicity and protection efficacy compared to whole-pathogen vaccines. Here, we present an approach aimed at bridging this disadvantage that is based on synergistic collaboration between patt...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Vaccines (Basel)
المؤلفون الرئيسيون: Tukhvatulin, Amir, Dzharullaeva, Alina, Erokhova, Alina, Zemskaya, Anastasia, Balyasin, Maxim, Ozharovskaia, Tatiana, Zubkova, Olga, Shevlyagina, Natalia, Zhukhovitsky, Vladimir, Fedyakina, Irina, Pruss, Ivan, Shcheblyakov, Dmitry, Naroditsky, Boris, Logunov, Denis, Gintsburg, Alexander
التنسيق: Artigo
اللغة:Inglês
منشور في: MDPI 2020
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564367/
https://ncbi.nlm.nih.gov/pubmed/32927915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030519
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