Recent advances of antibody drug conjugates for clinical applications

Antibody drug conjugates (ADCs) normally compose of a humanized antibody and small molecular drug via a chemical linker. After decades of preclinical and clinical studies, a series of ADCs have been widely used for treating specific tumor types in the clinic such as brentuximab vedotin (Adcetris®) f...

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Bibliografiske detaljer
Udgivet i:Acta Pharm Sin B
Main Authors: Zhao, Pengxuan, Zhang, Yuebao, Li, Wenqing, Jeanty, Christopher, Xiang, Guangya, Dong, Yizhou
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564033/
https://ncbi.nlm.nih.gov/pubmed/33088681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.04.012
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