Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected with Klebsiella pneumoniae

Surfactant protein A (SP-A) plays an important role in innate immunity. The sex-dependent survival of infected SP-A knockout (KO) mice has been observed. Our goal was to study the impact of ozone (O(3)) and sex, as well as gonadal hormones, on the bronchoalveolar lavage (BAL) readouts and survival,...

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Veröffentlicht in:Microorganisms
Hauptverfasser: Gandhi, Chintan K., Mikerov, Anatoly N., Durrani, Faryal, Umstead, Todd M., Hu, Sanmei, Wang, Guirong, Phelps, David S., Floros, Joanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563396/
https://ncbi.nlm.nih.gov/pubmed/32899781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8091354
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