Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (−/−) mice

Female mice exhibited higher survival rate than males after pneumonia, with a reversal of this pattern following ozone exposure. Surfactant protein A (SP-A) plays an important role in innate immunity and SP-A (−/−) mice were more susceptible to pneumonia than wild type mice. Here, we investigated un...

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Main Authors: Mikerov, Anatoly N., Hu, Sanmei, Durrani, Faryal, Gan, Xiaozhuang, Wang, Guirong, Umstead, Todd M., Phelps, David S., Floros, Joanna
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608432/
https://ncbi.nlm.nih.gov/pubmed/22285567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2012.01.005
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