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Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella pneumoniae infection

BACKGROUND: Survival of mice after K. pneumoniae infection and phagocytosis by alveolar macrophages (AMs), in the presence or absence of ozone (O(3)) exposure prior to infection is sex dependent. OBJECTIVES: Study the role of gonadal hormones, 5α-dihydrotestosterone (DHT) and 17β-estradiol (E(2)) on...

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Detalhes bibliográficos
Main Authors: Durrani, Faryal, Phelps, David S, Weisz, Judith, Silveyra, Patricia, Hu, Sanmei, Mikerov, Anatoly N, Floros, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651915/
https://ncbi.nlm.nih.gov/pubmed/22394250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902148.2011.654045
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