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Synthetic Notch-Receptor-Mediated Transmission of a Transient Signal into Permanent Information via CRISPR/Cas9-Based Genome Editing

Synthetic receptor biology and genome editing are emerging techniques, both of which are currently beginning to be used in preclinical and clinical applications. We were interested in whether a combination of these techniques approaches would allow for the generation of a novel type of reporter cell...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Sgodda, Malte, Alfken, Susanne, Schambach, Axel, Eggenschwiler, Reto, Fidzinski, Pawel, Hummel, Michael, Cantz, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563181/
https://ncbi.nlm.nih.gov/pubmed/32825374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091929
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