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Atomic-Level Characterization of the Methadone-Stabilized Active Conformation of µ-Opioid Receptor
Methadone is a synthetic opioid agonist with notoriously unique properties, such as lower abuse liability and induced relief of withdrawal symptoms and drug cravings, despite acting on the same opioid receptors triggered by classic opioids—in particular the µ-opioid receptor (MOR). Its distinct phar...
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| Veröffentlicht in: | Mol Pharmacol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7562981/ https://ncbi.nlm.nih.gov/pubmed/32680919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.119.119339 |
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