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Dynamic and Kinetic Elements of µ-Opioid Receptor Functional Selectivity
While the therapeutic effect of opioids analgesics is mainly attributed to µ-opioid receptor (MOR) activation leading to G protein signaling, their side effects have mostly been linked to β-arrestin signaling. To shed light on the dynamic and kinetic elements underlying MOR functional selectivity, w...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5595830/ https://ncbi.nlm.nih.gov/pubmed/28900175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11483-8 |
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