Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

Hyperinflation contributes to dyspnea intensity in COPD. Little is known about the molecular mechanisms underlying hyperinflation and how inhaled corticosteroids (ICS) affect this important aspect of COPD pathophysiology. To investigate the effect of ICS/long-acting β(2)-agonist (LABA) treatment on...

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發表在:Sci Rep
Main Authors: Faiz, Alen, Imkamp, Kai, van der Wiel, Erica, Boudewijn, Ilse M., Koppelman, Gerard H., Brandsma, Corry-Anke, Kerstjens, Huib A. M., Timens, Wim, Vroegop, Sebastiaan, Pasma, Henk R., Boersma, Wim G., Wielders, Pascal, van den Elshout, Frank, Mansour, Khaled, Steiling, Katrina, Spira, Avrum, Lenburg, Marc E., Heijink, Irene H., Postma, Dirkje S., van den Berge, Maarten
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562702/
https://ncbi.nlm.nih.gov/pubmed/33060632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72551-0
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