Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

Hyperinflation contributes to dyspnea intensity in COPD. Little is known about the molecular mechanisms underlying hyperinflation and how inhaled corticosteroids (ICS) affect this important aspect of COPD pathophysiology. To investigate the effect of ICS/long-acting β(2)-agonist (LABA) treatment on...

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Опубликовано в: :Sci Rep
Главные авторы: Faiz, Alen, Imkamp, Kai, van der Wiel, Erica, Boudewijn, Ilse M., Koppelman, Gerard H., Brandsma, Corry-Anke, Kerstjens, Huib A. M., Timens, Wim, Vroegop, Sebastiaan, Pasma, Henk R., Boersma, Wim G., Wielders, Pascal, van den Elshout, Frank, Mansour, Khaled, Steiling, Katrina, Spira, Avrum, Lenburg, Marc E., Heijink, Irene H., Postma, Dirkje S., van den Berge, Maarten
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562702/
https://ncbi.nlm.nih.gov/pubmed/33060632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72551-0
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