Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

Influenza viruses (Flu) are responsible for seasonal epidemics causing high rates of morbidity, which can dramatically increase during severe pandemic outbreaks. Antiviral drugs are an indispensable weapon to treat infected people and reduce the impact on human health, nevertheless anti-Flu armament...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Eur J Med Chem
Main Authors: Massari, Serena, Bertagnin, Chiara, Pismataro, Maria Chiara, Donnadio, Anna, Nannetti, Giulio, Felicetti, Tommaso, Di Bona, Stefano, Nizi, Maria Giulia, Tensi, Leonardo, Manfroni, Giuseppe, Loza, Maria Isabel, Sabatini, Stefano, Cecchetti, Violetta, Brea, Jose, Goracci, Laura, Loregian, Arianna, Tabarrini, Oriana
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Masson SAS. 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561591/
https://ncbi.nlm.nih.gov/pubmed/33328103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112944
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki