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ADMET profile and virtual screening of plant and microbial natural metabolites as SARS-CoV-2 S1 glycoprotein receptor binding domain and main protease inhibitors

In an attempt to search for selective inhibitors against the SARS-CoV-2 which caused devastating of lives and livelihoods across the globe, 415 natural metabolites isolated from several plants, fungi and bacteria, belonging to different classes, were investigated. The drug metabolism and safety prof...

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Dettagli Bibliografici
Pubblicato in:Eur J Pharmacol
Autori principali: Padhi, Srichandan, Masi, Marco, Chourasia, Rounak, Rajashekar, Yallappa, Rai, Amit Kumar, Evidente, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V. 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561576/
https://ncbi.nlm.nih.gov/pubmed/33069672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173648
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