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ADMET profile and virtual screening of plant and microbial natural metabolites as SARS-CoV-2 S1 glycoprotein receptor binding domain and main protease inhibitors

In an attempt to search for selective inhibitors against the SARS-CoV-2 which caused devastating of lives and livelihoods across the globe, 415 natural metabolites isolated from several plants, fungi and bacteria, belonging to different classes, were investigated. The drug metabolism and safety prof...

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Библиографические подробности
Опубликовано в: :Eur J Pharmacol
Главные авторы: Padhi, Srichandan, Masi, Marco, Chourasia, Rounak, Rajashekar, Yallappa, Rai, Amit Kumar, Evidente, Antonio
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier B.V. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561576/
https://ncbi.nlm.nih.gov/pubmed/33069672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2020.173648
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