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Dynamics and Molecular Mechanisms of p53 Transcriptional Activation
The “guardian of the genome”, p53, functions as a tumor suppressor that responds to cell stressors such as DNA damage, hypoxia, and tumor formation by inducing cell-cycle arrest, senescence, or apoptosis. Mutation of p53 disrupts its tumor suppressor function, leading to various types of human cance...
Gorde:
| Argitaratua izan da: | Biochemistry |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7560988/ https://ncbi.nlm.nih.gov/pubmed/30388364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01005 |
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