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Enhancing Virtual Screening Performance of Protein Kinases with Molecular Dynamics Simulations

In silico virtual screening (VS) is a powerful hit identification technique used in drug discovery projects that aims to effectively distinguish true actives from inactive or decoy molecules. To better capture the dynamic behavior of protein drug targets, compound databases may be screened against a...

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Bibliografische gegevens
Gepubliceerd in:J Chem Inf Model
Hoofdauteurs: Offutt, Tavina L., Swift, Robert V., Amaro, Rommie E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323360/
https://ncbi.nlm.nih.gov/pubmed/27662181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.6b00261
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