A strategy to incorporate prior knowledge into correlation network cutoff selection

Correlation networks are frequently used to statistically extract biological interactions between omics markers. Network edge selection is typically based on the statistical significance of the correlation coefficients. This procedure, however, is not guaranteed to capture biological mechanisms. We...

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Publicat a:Nat Commun
Autors principals: Benedetti, Elisa, Pučić-Baković, Maja, Keser, Toma, Gerstner, Nathalie, Büyüközkan, Mustafa, Štambuk, Tamara, Selman, Maurice H. J., Rudan, Igor, Polašek, Ozren, Hayward, Caroline, Al-Amin, Hassen, Suhre, Karsten, Kastenmüller, Gabi, Lauc, Gordan, Krumsiek, Jan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560866/
https://ncbi.nlm.nih.gov/pubmed/33056991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18675-3
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