A strategy to incorporate prior knowledge into correlation network cutoff selection

Correlation networks are frequently used to statistically extract biological interactions between omics markers. Network edge selection is typically based on the statistical significance of the correlation coefficients. This procedure, however, is not guaranteed to capture biological mechanisms. We...

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Udgivet i:Nat Commun
Main Authors: Benedetti, Elisa, Pučić-Baković, Maja, Keser, Toma, Gerstner, Nathalie, Büyüközkan, Mustafa, Štambuk, Tamara, Selman, Maurice H. J., Rudan, Igor, Polašek, Ozren, Hayward, Caroline, Al-Amin, Hassen, Suhre, Karsten, Kastenmüller, Gabi, Lauc, Gordan, Krumsiek, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560866/
https://ncbi.nlm.nih.gov/pubmed/33056991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18675-3
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