Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

Joint modeling of a number of phenotypes using multivariate methods has often been neglected in genome-wide association studies and if used, replication has not been sought. Modern omics technologies allow characterization of functional phenomena using a large number of related phenotype measures, w...

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Publicat a:Nat Commun
Autors principals: Shen, Xia, Klarić, Lucija, Sharapov, Sodbo, Mangino, Massimo, Ning, Zheng, Wu, Di, Trbojević-Akmačić, Irena, Pučić-Baković, Maja, Rudan, Igor, Polašek, Ozren, Hayward, Caroline, Spector, Timothy D., Wilson, James F., Lauc, Gordan, Aulchenko, Yurii S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587582/
https://ncbi.nlm.nih.gov/pubmed/28878392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00453-3
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