Glycosylation of Immunoglobulin G: Role of Genetic and Epigenetic Influences

OBJECTIVE: To determine the extent to which genetic and epigenetic factors contribute to variations in glycosylation of immunoglobulin G (IgG) in humans. METHODS: 76  N-glycan traits in circulating IgG were analyzed by UPLC in 220 monozygotic and 310 dizygotic twin pairs from TwinsUK. A classical tw...

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Detalhes bibliográficos
Main Authors: Menni, Cristina, Keser, Toma, Mangino, Massimo, Bell, Jordana T., Erte, Idil, Akmačić, Irena, Vučković, Frano, Pučić Baković, Maja, Gornik, Olga, McCarthy, Mark I., Zoldoš, Vlatka, Spector, Tim D., Lauc, Gordan, Valdes, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855797/
https://ncbi.nlm.nih.gov/pubmed/24324808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082558
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