A genetic memory initiates the epigenetic loop necessary to preserve centromere position

Centromeres are built on repetitive DNA sequences (CenDNA) and a specific chromatin enriched with the histone H3 variant CENP‐A, the epigenetic mark that identifies centromere position. Here, we interrogate the importance of CenDNA in centromere specification by developing a system to rapidly remove...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Hoffmann, Sebastian, Izquierdo, Helena M, Gamba, Riccardo, Chardon, Florian, Dumont, Marie, Keizer, Veer, Hervé, Solène, McNulty, Shannon M, Sullivan, Beth A, Manel, Nicolas, Fachinetti, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560200/
https://ncbi.nlm.nih.gov/pubmed/32945564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105505
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