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CENP-A is dispensable for mitotic centromere function after initial centromere/kinetochore assembly
Human centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive alphoid DNA sequences. By inducing rapid, complete degradation of endogenous CENP-A, we now demonstrate that once the first steps of centromere assembly have been completed in G1/S, continue...
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| Опубликовано в: : | Cell Rep |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5134894/ https://ncbi.nlm.nih.gov/pubmed/27880912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.084 |
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