CENP-A is dispensable for mitotic centromere function after initial centromere/kinetochore assembly

Human centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive alphoid DNA sequences. By inducing rapid, complete degradation of endogenous CENP-A, we now demonstrate that once the first steps of centromere assembly have been completed in G1/S, continue...

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Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Hoffmann, S, Dumont, M, Barra, V., Ly, P, Nechemia-Arbely, Y, McMahon, M.A., Hervé, S., Cleveland, DW, Fachinetti, D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134894/
https://ncbi.nlm.nih.gov/pubmed/27880912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.084
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