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A metabolite binding protein moonlights as a bile‐responsive chaperone

Bile salts are secreted into the gastrointestinal tract to aid in the absorption of lipids. In addition, bile salts show potent antimicrobial activity in part by mediating bacterial protein unfolding and aggregation. Here, using a protein folding sensor, we made the surprising discovery that the Esc...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Lee, Changhan, Betschinger, Patrick, Wu, Kevin, Żyła, Dawid S, Glockshuber, Rudi, Bardwell, James CA
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560199/
https://ncbi.nlm.nih.gov/pubmed/32882062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104231
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