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A metabolite binding protein moonlights as a bile‐responsive chaperone

Bile salts are secreted into the gastrointestinal tract to aid in the absorption of lipids. In addition, bile salts show potent antimicrobial activity in part by mediating bacterial protein unfolding and aggregation. Here, using a protein folding sensor, we made the surprising discovery that the Esc...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Lee, Changhan, Betschinger, Patrick, Wu, Kevin, Żyła, Dawid S, Glockshuber, Rudi, Bardwell, James CA
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560199/
https://ncbi.nlm.nih.gov/pubmed/32882062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104231
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