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Latent-space embedding of expression data identifies gene signatures from sputum samples of asthmatic patients

BACKGROUND: The pathogenesis of asthma is a complex process involving multiple genes and pathways. Identifying biomarkers from asthma datasets, especially those that include heterogeneous subpopulations, is challenging. Potentially, autoencoders provide ideal frameworks for such tasks as they can em...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Lou, Shaoke, Li, Tianxiao, Spakowicz, Daniel, Yan, Xiting, Chupp, Geoffrey Lowell, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560063/
https://ncbi.nlm.nih.gov/pubmed/33059594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03785-y
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