Approaches for integrating heterogeneous RNA-seq data reveal cross-talk between microbes and genes in asthmatic patients

Sputum induction is a non-invasive method to evaluate the airway environment, particularly for asthma. RNA sequencing (RNA-seq) of sputum samples can be challenging to interpret due to the complex and heterogeneous mixtures of human cells and exogenous (microbial) material. In this study, we develop...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Spakowicz, Daniel, Lou, Shaoke, Barron, Brian, Gomez, Jose L., Li, Tianxiao, Liu, Qing, Grant, Nicole, Yan, Xiting, Hoyd, Rebecca, Weinstock, George, Chupp, Geoffrey L., Gerstein, Mark
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310008/
https://ncbi.nlm.nih.gov/pubmed/32571363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02033-z
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