Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia

BACKGROUND: Polyamine catabolism plays a key role in maintaining intracellular polyamine pools, yet its physiological significance is largely unexplored. Here, we report that the disruption of polyamine catabolism leads to severe cerebellar damage and ataxia, demonstrating the fundamental role of po...

詳細記述

保存先:
書誌詳細
出版年:J Neuroinflammation
主要な著者: Zahedi, Kamyar, Brooks, Marybeth, Barone, Sharon, Rahmati, Negah, Murray Stewart, Tracy, Dunworth, Matthew, Destefano-Shields, Christina, Dasgupta, Nupur, Davidson, Steve, Lindquist, Diana M., Fuller, Christine E., Smith, Roger D., Cleveland, John L., Casero, Robert A., Soleimani, Manoocher
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559641/
https://ncbi.nlm.nih.gov/pubmed/33054763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01955-6
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料