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Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors

Failure to recognize important features of a drug’s pharmacokinetic characteristics is a key cause of inappropriate dose and schedule selection, and can lead to reduced efficacy and increased rate of adverse drug reactions requiring medical intervention. As oral chemotherapeutic agents, tyrosine kin...

詳細記述

保存先:
書誌詳細
出版年:Pharmaceutics
主要な著者: Garrison, Dominique A., Talebi, Zahra, Eisenmann, Eric D., Sparreboom, Alex, Baker, Sharyn D.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559291/
https://ncbi.nlm.nih.gov/pubmed/32916864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12090856
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