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Inhibition of OATP-1B1 and OATP-1B3 by tyrosine kinase inhibitors
BACKGROUND: The potential of tyrosine kinase inhibitors (TKIs) interacting with other therapeutics through hepatic uptake transporter inhibition has not been fully delineated in drug-drug interactions (DDIs). This study was designed to estimate the half-maximal inhibitory concentration (IC(50)) valu...
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Foilsithe in: | Drug Metabol Drug Interact |
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Main Authors: | , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2014
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407688/ https://ncbi.nlm.nih.gov/pubmed/24807167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/dmdi-2014-0014 |
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