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Persistent Sox9 expression in hypertrophic chondrocytes suppresses transdifferentiation into osteoblasts
Longitudinal bone growth is driven by endochondral ossification, a process in which cartilage tissue is generated by growth plate chondrocytes and then remodeled into bone by osteoblasts. In the postnatal growth plate, as hypertrophic chondrocytes approach the chondro-osseous junction, they may unde...
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| Publicado no: | Bone |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7558415/ https://ncbi.nlm.nih.gov/pubmed/31121357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.05.027 |
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