Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway

Meteorin-like (METRNL) protein is a newly identified myokine that functions to modulate energy expenditure and inflammation in adipose tissue. Herein, we aim to investigate the potential role and molecular basis of METRNL in doxorubicin (DOX)-induced cardiotoxicity. METRNL was found to be abundantly...

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Опубликовано в: :Redox Biol
Главные авторы: Hu, Can, Zhang, Xin, Song, Peng, Yuan, Yu-Pei, Kong, Chun-Yan, Wu, Hai-Ming, Xu, Si-Chi, Ma, Zhen-Guo, Tang, Qi-Zhu
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7558217/
https://ncbi.nlm.nih.gov/pubmed/33045622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101747
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