Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription

Protein arginine methyltransferase 5 (PRMT5) is an important type II arginine methyltransferase that can play roles in cancers in a highly tissue-specific manner, but its role in the carcinogenesis and metastasis of head and neck squamous cell carcinoma (HNSCC) remains unclear. Here, we detected PRM...

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Publicado en:Neoplasia
Autores principales: Fan, Zhaona, He, Lihong, Li, Mianxiang, Cao, Ruoyan, Deng, Miao, Ping, Fan, Liang, Xueyi, He, Yuan, Wu, Tong, Tao, Xiaoan, Xu, Jian, Cheng, Bin, Xia, Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2020
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Original article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557877/
https://ncbi.nlm.nih.gov/pubmed/33045527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.09.004
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