Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6

BACKGROUND & AIMS: Many genetic and environmental factors, including family history, dietary fat, and inflammation, increase risk for colon cancer development. Peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear receptor that regulates systemic lipid homeostasis. We explored th...

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Publicado en:Gastroenterology
Autores principales: Luo, Yuhong, Xie, Cen, Brocker, Chad N., Fan, Jie, Wu, Xuan, Feng, Lijin, Wang, Qiong, Zhao, Jie, Lu, Dasheng, Tandon, Mayank, Cam, Maggie, Krausz, Kristopher W., Liu, Weiwei, Gonzalez, Frank J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388731/
https://ncbi.nlm.nih.gov/pubmed/31154022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.05.057
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