Clearing of Foreign Episomal DNA from Human Cells by CRISPRa-Mediated Activation of Cytidine Deaminases

Restriction of foreign DNA is a fundamental defense mechanism required for maintaining genomic stability and proper function of mammalian cells. APOBEC cytidine deaminases are crucial effector molecules involved in clearing pathogenic DNA of viruses and other microorganisms and improperly localized...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Brezgin, Sergey, Kostyusheva, Anastasiya, Ponomareva, Natalia, Volia, Viktoriia, Goptar, Irina, Nikiforova, Anastasiya, Shilovskiy, Igor, Smirnov, Valery, Kostyushev, Dmitry, Chulanov, Vladimir
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557733/
https://ncbi.nlm.nih.gov/pubmed/32962129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186865
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