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CoGAPS 3: Bayesian non-negative matrix factorization for single-cell analysis with asynchronous updates and sparse data structures

BACKGROUND: Bayesian factorization methods, including Coordinated Gene Activity in Pattern Sets (CoGAPS), are emerging as powerful analysis tools for single cell data. However, these methods have greater computational costs than their gradient-based counterparts. These costs are often prohibitive fo...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Sherman, Thomas D., Gao, Tiger, Fertig, Elana J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556974/
https://ncbi.nlm.nih.gov/pubmed/33054706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03796-9
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