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The Expression of Phospho-AKT, Phospho-mTOR, and PTEN in Extrahepatic Cholangiocarcinoma

PURPOSE: The protein kinase B (AKT) pathway plays a key role in the regulation of cellular survival, apoptosis, and protein translation, and has been shown to have prognostic significance in a number of cancers. We sought to define its role in extrahepatic cholangiocarcinoma. EXPERIMENTAL DESIGN: Tw...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Chung, Joon-Yong, Hong, Seung-Mo, Choi, Byeong Yeob, Cho, HyungJun, Yu, Eunsil, Hewitt, Stephen M.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556734/
https://ncbi.nlm.nih.gov/pubmed/19147772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1084
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