Structural basis for selectivity in a highly reducing type II polyketide synthase

In type II polyketide synthases (PKSs), the ketosynthase-chain length factor (KS-CLF) complex catalyzes polyketide chain elongation with the acyl carrier protein (ACP). Highly reducing type II PKSs, represented by IgaPKS, produce polyene structures instead of the well-known aromatic skeletons. Here,...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem Biol
Asıl Yazarlar: Du, Danyao, Katsuyama, Yohei, Horiuchi, Masanobu, Fushinobu, Shinya, Chen, Aochiu, Davis, Tony D., Burkart, Michael D., Ohnishi, Yasuo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556716/
https://ncbi.nlm.nih.gov/pubmed/32367018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0530-0
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