XPO1 regulates erythroid differentiation and is a new target for the treatment of β-thalassemia

β-thalassemia major (β-TM) is an inherited hemoglobinopathy caused by a quantitative defect in the synthesis of β-globin chains of hemoglobin, leading to the accumulation of free a-globin chains that aggregate and cause ineffective erythropoiesis. We have previously demonstrated that terminal erythr...

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Publicado no:Haematologica
Main Authors: Guillem, Flavia, Dussiot, Michaël, Colin, Elia, Suriyun, Thunwarat, Arlet, Jean Benoit, Goudin, Nicolas, Marcion, Guillaume, Seigneuric, Renaud, Causse, Sebastien, Gonin, Patrick, Gastou, Marc, Deloger, Marc, Rossignol, Julien, Lamarque, Mathilde, Choucair, Zakia Belaid, Gautier, Emilie Fleur, Ducamp, Sarah, Vandekerckhove, Julie, Moura, Ivan C., Maciel, Thiago Trovati, Garrido, Carmen, An, Xiuli, Mayeux, Patrick, Mohandas, Narla, Courtois, Geneviève, Hermine, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Fondazione Ferrata Storti 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556489/
https://ncbi.nlm.nih.gov/pubmed/33054049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.210054
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