XPO1 regulates erythroid differentiation and is a new target for the treatment of β-thalassemia

β-thalassemia major (β-TM) is an inherited hemoglobinopathy caused by a quantitative defect in the synthesis of β-globin chains of hemoglobin, leading to the accumulation of free a-globin chains that aggregate and cause ineffective erythropoiesis. We have previously demonstrated that terminal erythr...

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Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Guillem, Flavia, Dussiot, Michaël, Colin, Elia, Suriyun, Thunwarat, Arlet, Jean Benoit, Goudin, Nicolas, Marcion, Guillaume, Seigneuric, Renaud, Causse, Sebastien, Gonin, Patrick, Gastou, Marc, Deloger, Marc, Rossignol, Julien, Lamarque, Mathilde, Choucair, Zakia Belaid, Gautier, Emilie Fleur, Ducamp, Sarah, Vandekerckhove, Julie, Moura, Ivan C., Maciel, Thiago Trovati, Garrido, Carmen, An, Xiuli, Mayeux, Patrick, Mohandas, Narla, Courtois, Geneviève, Hermine, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Fondazione Ferrata Storti 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556489/
https://ncbi.nlm.nih.gov/pubmed/33054049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.210054
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