AMP-independent activator of AMPK for treatment of mitochondrial disorders

Mitochondrial diseases are a clinically heterogenous group of disorders caused by respiratory chain dysfunction and associated with progressive, multi-systemic phenotype. There is no effective treatment or cure, and no FDA-approved drug for treating mitochondrial disease. To identify and characteriz...

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Bibliographic Details
Published in:PLoS One
Main Authors: Moore, Tereza, Yanes, Rolando E., Calton, Melissa A., Vollrath, Douglas, Enns, Gregory M., Cowan, Tina M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556449/
https://ncbi.nlm.nih.gov/pubmed/33052980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240517
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