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Tumor burden, inflammation, and product attributes determine outcomes of axicabtagene ciloleucel in large B-cell lymphoma

ZUMA-1 demonstrated a high rate of durable response and a manageable safety profile with axicabtagene ciloleucel (axi-cel), an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, in patients with refractory large B-cell lymphoma. As previously reported, prespecified clinical covariates for sec...

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Bibliografski detalji
Izdano u:Blood Adv
Glavni autori: Locke, Frederick L., Rossi, John M., Neelapu, Sattva S., Jacobson, Caron A., Miklos, David B., Ghobadi, Armin, Oluwole, Olalekan O., Reagan, Patrick M., Lekakis, Lazaros J., Lin, Yi, Sherman, Marika, Better, Marc, Go, William Y., Wiezorek, Jeffrey S., Xue, Allen, Bot, Adrian
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556133/
https://ncbi.nlm.nih.gov/pubmed/33035333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002394
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